A novel Mcl1 variant inhibits apoptosis via increased Bim sequestration

Members of the Bcl-2 protein family are frequently deregulated in tumors as they critically control cell death induction in mammalian cells. Alterations of these proteins may cause resistance to chemotherapy-induced cell death and immune responses. By serendipity we cloned a variant of the anti-apop...

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Detalles Bibliográficos
Autores principales: Hagenbuchner, Judith, Kiechl-Kohlendorfer, Ursula, Obexer, Petra, Ausserlechner, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787154/
https://www.ncbi.nlm.nih.gov/pubmed/23872733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787154/
https://www.ncbi.nlm.nih.gov/pubmed/23872733

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