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HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness

Breast cancer is a heterogeneous disease that progresses to the critical hallmark of metastasis. In the present study, we show that the High Mobility Group A1 (HMGA1) protein plays a fundamental role in this process in basal-like breast cancer subtype. HMGA1 knockdown induces the mesenchymal to epit...

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Detalles Bibliográficos
Autores principales: Pegoraro, Silvia, Ros, Gloria, Piazza, Silvano, Sommaggio, Roberta, Ciani, Yari, Rosato, Antonio, Sgarra, Riccardo, Del Sal, Giannino, Manfioletti, Guidalberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787158/
https://www.ncbi.nlm.nih.gov/pubmed/23945276