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Cancer Metabolism: New Validated Targets for Drug Discovery

Recent studies in cancer metabolism directly implicate catabolic fibroblasts as a new rich source of i) energy and ii) biomass, for the growth and survival of anabolic cancer cells. Conversely, anabolic cancer cells upregulate oxidative mitochondrial metabolism, to take advantage of the abundant fib...

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Detalles Bibliográficos
Autores principales: Sotgia, Federica, Martinez-Outschoorn, Ubaldo E., Lisanti, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787159/
https://www.ncbi.nlm.nih.gov/pubmed/23896568