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The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration

Carbonic anhydrase IX is a hypoxia-induced transmembrane enzyme linked with solid tumors. It catalyzes the reversible hydration of CO(2) providing bicarbonate ions for intracellular neutralization and protons for extracellular acidosis, thereby supporting tumor cell survival and invasiveness. CA IX...

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Detalles Bibliográficos
Autores principales: Csaderova, Lucia, Debreova, Michaela, Radvak, Peter, Stano, Matej, Vrestiakova, Magdalena, Kopacek, Juraj, Pastorekova, Silvia, Svastova, Eliska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787331/
https://www.ncbi.nlm.nih.gov/pubmed/24101905
http://dx.doi.org/10.3389/fphys.2013.00271