Intracerebroventricular Administration of Amyloid β-protein Oligomers Selectively Increases Dorsal Hippocampal Dialysate Glutamate Levels in the Awake Rat

Extensive evidence supports an important role for soluble oligomers of the amyloid β-protein (Aβ) in Alzheimer's Disease pathogenesis. In the present study we combined intracerebroventricular (icv) injections with brain microdialysis technology in the fully conscious rat to assess the effects o...

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Detalles Bibliográficos
Autores principales: O'Shea, Sean D., Smith, Imelda M., McCabe, Olive M., Cronin, Michelle M., Walsh, Dominic M., O'Connor, William T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787453/
https://www.ncbi.nlm.nih.gov/pubmed/27873937
http://dx.doi.org/10.3390/s8117428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787453/
https://www.ncbi.nlm.nih.gov/pubmed/27873937
http://dx.doi.org/10.3390/s8117428

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