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Intracerebroventricular Administration of Amyloid β-protein Oligomers Selectively Increases Dorsal Hippocampal Dialysate Glutamate Levels in the Awake Rat
Extensive evidence supports an important role for soluble oligomers of the amyloid β-protein (Aβ) in Alzheimer's Disease pathogenesis. In the present study we combined intracerebroventricular (icv) injections with brain microdialysis technology in the fully conscious rat to assess the effects o...
Autores principales: | O'Shea, Sean D., Smith, Imelda M., McCabe, Olive M., Cronin, Michelle M., Walsh, Dominic M., O'Connor, William T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787453/ https://www.ncbi.nlm.nih.gov/pubmed/27873937 http://dx.doi.org/10.3390/s8117428 |
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