ATR/Mec1 prevents lethal meiotic recombination initiation on partially replicated chromosomes in budding yeast

During gamete formation, crossover recombination must occur on replicated DNA to ensure proper chromosome segregation in the first meiotic division. We identified a Mec1/ATR- and Dbf4-dependent replication checkpoint in budding yeast that prevents the earliest stage of recombination, the programmed...

Descripción completa

Detalles Bibliográficos
Autores principales: Blitzblau, Hannah G, Hochwagen, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787542/
https://www.ncbi.nlm.nih.gov/pubmed/24137535
http://dx.doi.org/10.7554/eLife.00844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787542/
https://www.ncbi.nlm.nih.gov/pubmed/24137535
http://dx.doi.org/10.7554/eLife.00844

Ejemplares similares