Cargando…
ATR/Mec1 prevents lethal meiotic recombination initiation on partially replicated chromosomes in budding yeast
During gamete formation, crossover recombination must occur on replicated DNA to ensure proper chromosome segregation in the first meiotic division. We identified a Mec1/ATR- and Dbf4-dependent replication checkpoint in budding yeast that prevents the earliest stage of recombination, the programmed...
Autores principales: | Blitzblau, Hannah G, Hochwagen, Andreas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787542/ https://www.ncbi.nlm.nih.gov/pubmed/24137535 http://dx.doi.org/10.7554/eLife.00844 |
Ejemplares similares
-
Separation of DNA Replication from the Assembly of Break-Competent Meiotic Chromosomes
por: Blitzblau, Hannah G., et al.
Publicado: (2012) -
Transcription dynamically patterns the meiotic chromosome-axis interface
por: Sun, Xiaoji, et al.
Publicado: (2015) -
Reduced dosage of the chromosome axis factor Red1 selectively disrupts the meiotic recombination checkpoint in Saccharomyces cerevisiae
por: Markowitz, Tovah E., et al.
Publicado: (2017) -
Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast
por: King, Grant A, et al.
Publicado: (2019) -
Budding Yeast Pch2, a Widely Conserved Meiotic Protein, Is Involved in the Initiation of Meiotic Recombination
por: Farmer, Sarah, et al.
Publicado: (2012)