TNFα Mediated IL-6 Secretion Is Regulated by JAK/STAT Pathway but Not by MEK Phosphorylation and AKT Phosphorylation in U266 Multiple Myeloma Cells

IL-6 and TNFα were significantly increased in the bone marrow aspirate samples of patients with active multiple myeloma (MM) compared to those of normal controls. Furthermore, MM patients with advanced aggressive disease had significantly higher levels of IL-6 and TNFα than those with MM in plateau...

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Detalles Bibliográficos
Autores principales: Lee, Chansu, Oh, Jeong-In, Park, Juwon, Choi, Jee-Hye, Bae, Eun-Kyung, Lee, Hyun Jung, Jung, Woo June, Lee, Dong Soon, Ahn, Kwang-Sung, Yoon, Sung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787550/
https://www.ncbi.nlm.nih.gov/pubmed/24151609
http://dx.doi.org/10.1155/2013/580135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787550/
https://www.ncbi.nlm.nih.gov/pubmed/24151609
http://dx.doi.org/10.1155/2013/580135

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