7,8-Dihydroxyflavone Suppresses Oxidative Stress-Induced Base Modification in DNA via Induction of the Repair Enzyme 8-Oxoguanine DNA Glycosylase-1

The modified guanine base 8-oxoguanine (8-oxoG) is abundantly produced by oxidative stress, can contribute to carcinogenesis, and can be removed from DNA by 8-oxoguanine DNA glycosylase-1 (OGG1), which acts as an 8-oxoG glycosylase and endonuclease. This study investigated the mechanism by which 7,8...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Ki Cheon, Lee, In Kyung, Kang, Kyoung Ah, Cha, Ji Won, Cho, Suk Ju, Na, Soo Young, Chae, Sungwook, Kim, Hye Sun, Kim, Suhkmann, Hyun, Jin Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787557/
https://www.ncbi.nlm.nih.gov/pubmed/24151624
http://dx.doi.org/10.1155/2013/863720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787557/
https://www.ncbi.nlm.nih.gov/pubmed/24151624
http://dx.doi.org/10.1155/2013/863720

Ejemplares similares