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Polymorphisms in the Human Cytochrome P450 and Arylamine N-Acetyltransferase: Susceptibility to Head and Neck Cancers

The occurrence of head and neck cancer (HNC) is associated with smoking and alcohol drinking. Tobacco smoking exposes smokers to a series of carcinogenic chemicals. Cytochrome P450 enzymes (CYP450s), such as CYP1A1, CYP1B1, and CYP2D6, usually metabolize carcinogens to their inactive derivatives, bu...

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Detalles Bibliográficos
Autores principales: Khlifi, Rim, Messaoud, Olfa, Rebai, Ahmed, Hamza-Chaffai, Amel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787584/
https://www.ncbi.nlm.nih.gov/pubmed/24151610
http://dx.doi.org/10.1155/2013/582768