Rapid Evolution to Blast Crisis Associated with a Q252H ABL1 Kinase Domain Mutation in e19a2 BCR-ABL1 Chronic Myeloid Leukaemia

A minority of chronic myeloid leukaemia (CML) patients express variant transcripts of which the e19a2 BCR-ABL1 fusion is the most common. Instances of tyrosine kinase inhibitor (TKI) resistance in e19a2 BCR-ABL1 CML patients have rarely been reported. A case of e19a2 BCR-ABL1 CML is described in who...

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Detalles Bibliográficos
Autores principales: McCarron, Sarah L., Maher, Karena, Kelly, Johanna, Ryan, Mary F., Langabeer, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787624/
https://www.ncbi.nlm.nih.gov/pubmed/24109527
http://dx.doi.org/10.1155/2013/490740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787624/
https://www.ncbi.nlm.nih.gov/pubmed/24109527
http://dx.doi.org/10.1155/2013/490740

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