p53/p21 Pathway Involved in Mediating Cellular Senescence of Bone Marrow-Derived Mesenchymal Stem Cells from Systemic Lupus Erythematosus Patients

Our and other groups have found that bone marrow-derived mesenchymal stem cells (BM-MSCs) from systemic lupus erythematosus (SLE) patients exhibited senescent behavior and are involved in the pathogenesis of SLE. Numerous studies have shown that activation of the p53/p21 pathway inhibits the prolife...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Zhifeng, Jiang, Jinxia, Tan, Wei, Xia, Yunfei, Cao, Haixia, Meng, Yan, Da, Zhanyun, Liu, Hong, Cheng, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787636/
https://www.ncbi.nlm.nih.gov/pubmed/24151513
http://dx.doi.org/10.1155/2013/134243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787636/
https://www.ncbi.nlm.nih.gov/pubmed/24151513
http://dx.doi.org/10.1155/2013/134243

Ejemplares similares