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p53/p21 Pathway Involved in Mediating Cellular Senescence of Bone Marrow-Derived Mesenchymal Stem Cells from Systemic Lupus Erythematosus Patients

Our and other groups have found that bone marrow-derived mesenchymal stem cells (BM-MSCs) from systemic lupus erythematosus (SLE) patients exhibited senescent behavior and are involved in the pathogenesis of SLE. Numerous studies have shown that activation of the p53/p21 pathway inhibits the prolife...

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Detalles Bibliográficos
Autores principales:	Gu, Zhifeng, Jiang, Jinxia, Tan, Wei, Xia, Yunfei, Cao, Haixia, Meng, Yan, Da, Zhanyun, Liu, Hong, Cheng, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787636/ https://www.ncbi.nlm.nih.gov/pubmed/24151513 http://dx.doi.org/10.1155/2013/134243

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