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Epigenetics and Autism

This review identifies mechanisms for altering DNA-histone interactions of cell chromatin to upregulate or downregulate gene expression that could serve as epigenetic targets for therapeutic interventions in autism. DNA methyltransferases (DNMTs) can phosphorylate histone H3 at T6. Aided by protein...

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Detalles Bibliográficos
Autores principales: Mbadiwe, Tafari, Millis, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787640/
https://www.ncbi.nlm.nih.gov/pubmed/24151554
http://dx.doi.org/10.1155/2013/826156