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Human Expression QTLs Are Enriched in Signals of Environmental Adaptation

Expression quantitative trait loci (eQTLs) have been found to be enriched in trait-associated single-nucleotide polymorphisms (SNPs). However, whether eQTLs are adaptive to different environmental factors and its relative evolutionary significance compared with nonsynonymous SNPs (NS SNPs) are still...

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Detalles Bibliográficos
Autores principales: Ye, Kaixiong, Lu, Jian, Raj, Srilakshmi Madhura, Gu, Zhenglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787676/
https://www.ncbi.nlm.nih.gov/pubmed/23960253
http://dx.doi.org/10.1093/gbe/evt124