HIPK2 catalytic activity and subcellular localization are regulated by activation-loop Y354 autophosphorylation

HIPK2 (homeodomain-interacting protein kinase-2) binds to and phosphorylates, at Ser and Thr residues, a large number of targets involved in cell division and cell fate decision in response to different physiological or stress stimuli. Inactivation of HIPK2 has been observed in human and mouse cance...

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Detalles Bibliográficos
Autores principales: Siepi, Francesca, Gatti, Veronica, Camerini, Serena, Crescenzi, Marco, Soddu, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787740/
https://www.ncbi.nlm.nih.gov/pubmed/23485397
http://dx.doi.org/10.1016/j.bbamcr.2013.02.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787740/
https://www.ncbi.nlm.nih.gov/pubmed/23485397
http://dx.doi.org/10.1016/j.bbamcr.2013.02.018

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