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Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis

The fungal cell possesses an essential carbohydrate cell wall. The outer layer, mannan, is formed by mannoproteins carrying highly mannosylated O- and N-linked glycans. Yeast mannan biosynthesis is initiated by a Golgi-located complex (M-Pol I) of two GT-62 mannosyltransferases, Mnn9p and Van1p, tha...

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Detalles Bibliográficos
Autores principales: Striebeck, Alexander, Robinson, David A., Schüttelkopf, Alexander W., van Aalten, Daan M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787745/
https://www.ncbi.nlm.nih.gov/pubmed/24026536
http://dx.doi.org/10.1098/rsob.130022