Cargando…

MHF1–2/CENP-S-X performs distinct roles in centromere metabolism and genetic recombination

The histone-fold proteins Mhf1/CENP-S and Mhf2/CENP-X perform two important functions in vertebrate cells. First, they are components of the constitutive centromere-associated network, aiding kinetochore assembly and function. Second, they work with the FANCM DNA translocase to promote DNA repair. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhattacharjee, Sonali, Osman, Fekret, Feeney, Laura, Lorenz, Alexander, Bryer, Claire, Whitby, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787749/
https://www.ncbi.nlm.nih.gov/pubmed/24026537
http://dx.doi.org/10.1098/rsob.130102