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Cytochrome bd-I in Escherichia coli is less sensitive than cytochromes bd-II or bo′' to inhibition by the carbon monoxide-releasing molecule, CORM-3()(): N-acetylcysteine reduces CO-RM uptake and inhibition of respiration

Background: CO-releasing molecules (CO-RMs) are potential therapeutic agents, able to deliver CO – a critical gasotransmitter – in biological environments. CO-RMs are also effective antimicrobial agents; although the mechanisms of action are poorly defined, haem-containing terminal oxidases are prim...

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Detalles Bibliográficos
Autores principales: Jesse, Helen E., Nye, Tacita L., McLean, Samantha, Green, Jeffrey, Mann, Brian E., Poole, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787766/
https://www.ncbi.nlm.nih.gov/pubmed/23624261
http://dx.doi.org/10.1016/j.bbapap.2013.04.019