miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer

GRP78, a major endoplasmic reticulum chaperone and signaling regulator, is commonly overexpressed in cancer. Moreover, induction of GRP78 by a variety of anti-cancer drugs, including histone deacetylase inhibitors, confers chemoresistance to cancer, thereby contributing to tumorigenesis. Thus, thera...

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Detalles Bibliográficos
Autores principales: Su, S-F, Chang, Y-W, Andreu-Vieyra, C, Fang, J Y, Yang, Z, Han, B, Lee, A S, Liang, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787795/
https://www.ncbi.nlm.nih.gov/pubmed/23085757
http://dx.doi.org/10.1038/onc.2012.483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787795/
https://www.ncbi.nlm.nih.gov/pubmed/23085757
http://dx.doi.org/10.1038/onc.2012.483

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