The dual inhibitory effect of thiostrepton on FoxM1 and EWS/FLI1 provides a novel therapeutic option for Ewing’s sarcoma

The poor prognosis of Ewing’s sarcoma (EWS), together with its high lethal recurrence rate and the side-effects of current treatments, call for novel targeted therapies with greater curative effectiveness and substantially reduced side-effects. The oncogenic chimeric protein EWS/FLI1 is the key mali...

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Detalles Bibliográficos
Autores principales: SENGUPTA, ANIRUDDHA, RAHMAN, MAHBUBUR, MATEO-LOZANO, SILVIA, TIRADO, OSCAR M., NOTARIO, VICENTE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787886/
https://www.ncbi.nlm.nih.gov/pubmed/23857410
http://dx.doi.org/10.3892/ijo.2013.2016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787886/
https://www.ncbi.nlm.nih.gov/pubmed/23857410
http://dx.doi.org/10.3892/ijo.2013.2016

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