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β-Elemene enhances susceptibility to cisplatin in resistant ovarian carcinoma cells via downregulation of ERCC-1 and XIAP and inactivation of JNK

β-Elemene is a promising new plant-derived drug with broad-spectrum anticancer activity. It also increases cisplatin cytotoxicity and enhances cisplatin sensitivity in resistant human carcinoma cells. However, little is known about the mechanism of its action. To explore the potential therapeutic ap...

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Detalles Bibliográficos
Autores principales: LI, QUENTIN Q., LEE, REBECCA X., LIANG, HUASHENG, WANG, GANGDUO, LI, JUELI M., ZHONG, YUHUA, REED, EDDIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787889/
https://www.ncbi.nlm.nih.gov/pubmed/23817665
http://dx.doi.org/10.3892/ijo.2013.1996