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Four MicroRNAs Promote Prostate Cell Proliferation with Regulation of PTEN and Its Downstream Signals In Vitro

BACKGROUND: Phosphatase and tensin homologue (PTEN), as a tumor suppressor, plays vital roles in tumorigenesis and progression of prostate cancer. However, the mechanisms of PTEN regulation still need further investigation. We here report that a combination of four microRNAs (miR-19b, miR-23b, miR-2...

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Detalles Bibliográficos
Autores principales: Tian, Ling, Fang, Yu-xiang, Xue, Jing-lun, Chen, Jin-zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787937/
https://www.ncbi.nlm.nih.gov/pubmed/24098737
http://dx.doi.org/10.1371/journal.pone.0075885