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Soluble Human Leukocyte Antigen-G5 Activates Extracellular Signal-Regulated Protein Kinase Signaling and Stimulates Trophoblast Invasion

Soluble human leukocyte antigen-G (HLA-G) is a non-classical class Ib HLA molecule that is secreted from blastocysts. Soluble HLA-G modulates the immune tolerance of the mother and can be used as a prognostic factor for the clinical pregnancy rate. However, the underlying mechanism of how soluble HL...

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Detalles Bibliográficos
Autores principales: Guo, YiFan, Lee, Cheuk-Lun, So, Kam-Hei, Gao, Jing, Yeung, William S. B., Yao, YuanQing, Lee, Kai-Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787956/
https://www.ncbi.nlm.nih.gov/pubmed/24098421
http://dx.doi.org/10.1371/journal.pone.0076023