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Transgenic Mosquitoes Expressing a Phospholipase A(2) Gene Have a Fitness Advantage When Fed Plasmodium falciparum-Infected Blood

BACKGROUND: Genetically modified mosquitoes have been proposed as an alternative strategy to reduce the heavy burden of malaria. In recent years, several proof-of-principle experiments have been performed that validate the idea that mosquitoes can be genetically modified to become refractory to mala...

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Detalles Bibliográficos
Autores principales: Smith, Ryan C., Kizito, Christopher, Rasgon, Jason L., Jacobs-Lorena, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788000/
https://www.ncbi.nlm.nih.gov/pubmed/24098427
http://dx.doi.org/10.1371/journal.pone.0076097