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Mutations in Non-Acid Patch Residues Disrupt H2A.Z’s Association with Chromatin through Multiple Mechanisms

The incorporation of histone variants into nucleosomes is a critical mechanism for regulating essential DNA-templated processes and for establishing distinct chromatin architectures with specialised functions. H2A.Z is an evolutionarily conserved H2A variant that has diverse roles in transcriptional...

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Detalles Bibliográficos
Autores principales: Wood, Thomas J., Thistlethwaite, Angela, Harris, Michael R., Lovell, Simon C., Millar, Catherine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788105/
https://www.ncbi.nlm.nih.gov/pubmed/24098487
http://dx.doi.org/10.1371/journal.pone.0076394