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Oligomerization Interface of RAGE Receptor Revealed by MS-Monitored Hydrogen Deuterium Exchange

Activation of the receptor for advanced glycation end products (RAGE) leads to a chronic proinflammatory signal, affecting patients with a variety of diseases. Potentially beneficial modification of RAGE activity requires understanding the signal transduction mechanism at the molecular level. The li...

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Detalles Bibliográficos
Autores principales: Sitkiewicz, Ewa, Tarnowski, Krzysztof, Poznański, Jarosław, Kulma, Magdalena, Dadlez, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788119/
https://www.ncbi.nlm.nih.gov/pubmed/24098480
http://dx.doi.org/10.1371/journal.pone.0076353