Up-Regulation of SOX9 in Sertoli Cells from Testiculopathic Patients Accounts for Increasing Anti-Mullerian Hormone Expression via Impaired Androgen Receptor Signaling

BACKGROUND: Testosterone provokes Sertoli cell maturation and represses AMH production. In adult patients with Sertoli-cells-only syndrome (SCOS) and androgen insensitivity syndrome (AIS), high level of AMH expression is detected in Sertoli cells due to defect of androgen/AR signaling. OBJECTIVE: We...

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Detalles Bibliográficos
Autores principales: Lan, Kuo-Chung, Chen, Yen-Ta, Chang, Chawnshang, Chang, Yung-Chiao, Lin, Hsin-Jung, Huang, Ko-En, Kang, Hong-Yo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788123/
https://www.ncbi.nlm.nih.gov/pubmed/24098470
http://dx.doi.org/10.1371/journal.pone.0076303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788123/
https://www.ncbi.nlm.nih.gov/pubmed/24098470
http://dx.doi.org/10.1371/journal.pone.0076303

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