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Amplified Inhibition of Stellate Cell Activation Pathways by PPAR-γ, RAR and RXR Agonists

Peroxisome proliferator activator receptors (PPAR) ligands such as 15-Δ12,13-prostaglandin L(2) [PJ] and all trans retinoic acid (ATRA) have been shown to inhibit the development of liver fibrosis. The role of ligands of retinoic X receptor (RXR) and its ligand, 9-cis, is less clear. The purpose of...

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Detalles Bibliográficos
Autores principales: Sharvit, Efrat, Abramovitch, Shirley, Reif, Shimon, Bruck, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788137/
https://www.ncbi.nlm.nih.gov/pubmed/24098526
http://dx.doi.org/10.1371/journal.pone.0076541