Acid Ceramidase Promotes Nuclear Export of PTEN through Sphingosine 1-Phosphate Mediated Akt Signaling

The tumor suppressor PTEN is now understood to regulate cellular processes at the cytoplasmic membrane, where it classically regulates PI3K signaling, as well as in the nucleus where multiple roles in controlling cell cycle and genome stability have been elucidated. Mechanisms that dictate nuclear i...

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Detalles Bibliográficos
Autores principales: Beckham, Thomas H., Cheng, Joseph C., Lu, Ping, Marrison, S. Tucker, Norris, James S., Liu, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788144/
https://www.ncbi.nlm.nih.gov/pubmed/24098536
http://dx.doi.org/10.1371/journal.pone.0076593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788144/
https://www.ncbi.nlm.nih.gov/pubmed/24098536
http://dx.doi.org/10.1371/journal.pone.0076593

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