Influence of N-Myristylation and Ligand Binding on the Flexibility of the Catalytic Subunit of Protein Kinase A

[Image: see text] The catalytic (C) subunit of protein kinase A is regulated in part by cotranslational N-myristylation and ligand binding. Using a combination of time-resolved fluorescence anisotropy and molecular dynamics (MD) simulations, we characterized the effect of N-myristylation and ligand...

Descripción completa

Detalles Bibliográficos
Autores principales: Bastidas, Adam C., Pierce, Levi C., Walker, Ross C., Johnson, David A., Taylor, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788587/
https://www.ncbi.nlm.nih.gov/pubmed/24003983
http://dx.doi.org/10.1021/bi400575k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788587/
https://www.ncbi.nlm.nih.gov/pubmed/24003983
http://dx.doi.org/10.1021/bi400575k

Ejemplares similares