DNA Methylation Mediates Persistent Epileptiform Activity In Vitro and In Vivo

Epilepsy is a chronic brain disorder involving recurring seizures often precipitated by an earlier neuronal insult. The mechanisms that link the transient neuronal insult to the lasting state of epilepsy are unknown. Here we tested the possible role of DNA methylation in mediating long-term inductio...

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Detalles Bibliográficos
Autores principales: Machnes, Ziv M., Huang, Tony C. T., Chang, Philip K. Y., Gill, Raminder, Reist, Nicholas, Dezsi, Gabriella, Ozturk, Ezgi, Charron, Francois, O’Brien, Terence J., Jones, Nigel C., McKinney, R. Anne, Szyf, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788713/
https://www.ncbi.nlm.nih.gov/pubmed/24098468
http://dx.doi.org/10.1371/journal.pone.0076299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788713/
https://www.ncbi.nlm.nih.gov/pubmed/24098468
http://dx.doi.org/10.1371/journal.pone.0076299

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