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Simvastatin Ameliorates Liver Fibrosis via Mediating Nitric Oxide Synthase in Rats with Non-Alcoholic Steatohepatitis-Related Liver Fibrosis

BACKGROUND: Simvastatin exerts pleiotropic effects on cardiovascular system. However, its effect on non-alcoholic fatty liver disease, especially the liver fibrosis, remains obscure. We aimed to clarify the relationship between simvastatin and liver fibrosis both in vivo and in vitro. METHODS: A Hig...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Zhao, Caiyan, Zhou, Junying, Zhen, Zhen, Wang, Yadong, Shen, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788732/
https://www.ncbi.nlm.nih.gov/pubmed/24098525
http://dx.doi.org/10.1371/journal.pone.0076538