2-Bromopalmitate Reduces Protein Deacylation by Inhibition of Acyl-Protein Thioesterase Enzymatic Activities

S-acylation, the covalent attachment of palmitate and other fatty acids on cysteine residues, is a reversible post-translational modification that exerts diverse effects on protein functions. S-acylation is catalyzed by protein acyltransferases (PAT), while deacylation requires acyl-protein thioeste...

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Detalles Bibliográficos
Autores principales: Pedro, Maria P., Vilcaes, Aldo A., Tomatis, Vanesa M., Oliveira, Rafael G., Gomez, Guillermo A., Daniotti, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788759/
https://www.ncbi.nlm.nih.gov/pubmed/24098372
http://dx.doi.org/10.1371/journal.pone.0075232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788759/
https://www.ncbi.nlm.nih.gov/pubmed/24098372
http://dx.doi.org/10.1371/journal.pone.0075232

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