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Highly Sensitive Quantitative Real-Time PCR for the Detection of Plasmodium Liver-Stage Parasite Burden following Low-Dose Sporozoite Challenge

The pre-erythrocytic stages of Plasmodium spp. are increasingly recognised as ideal targets for prophylactic vaccines and drug treatments. Intense research efforts in the last decade have been focused on in vitro culture and in vivo detection and quantification of liver stage parasites to assess the...

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Detalles Bibliográficos
Autores principales: Schussek, Sophie, Groves, Penny L., Apte, Simon H., Doolan, Denise L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788780/
https://www.ncbi.nlm.nih.gov/pubmed/24098596
http://dx.doi.org/10.1371/journal.pone.0077811