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Serotonin 5-HT(2A) Receptor Activation Blocks TNF-α Mediated Inflammation In Vivo

Tumor necrosis factor alpha (TNF-α) plays a key role in inflammation, and its production and signaling contribute to many inflammatory related diseases. Recently, we discovered that selective activation of serotonin 5-HT(2A) receptors with the agonist (R)-DOI produces a super-potent blockade of proi...

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Detalles Bibliográficos
Autores principales: Nau, Felix, Yu, Bangning, Martin, David, Nichols, Charles D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788795/
https://www.ncbi.nlm.nih.gov/pubmed/24098382
http://dx.doi.org/10.1371/journal.pone.0075426