DNA Damage Repair Genes Controlling Human Papillomavirus (HPV) Episome Levels under Conditions of Stability and Extreme Instability

DNA damage response (DDR) genes and pathways controlling the stability of HPV episomal DNA are reported here. We set out to understand the mechanism by which a DNA-binding, N-methylpyrrole-imidazole hairpin polyamide (PA25) acts to cause the dramatic loss of HPV DNA from cells. Southern blots reveal...

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Detalles Bibliográficos
Autores principales: Edwards, Terri G., Vidmar, Thomas J., Koeller, Kevin, Bashkin, James K., Fisher, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788802/
https://www.ncbi.nlm.nih.gov/pubmed/24098381
http://dx.doi.org/10.1371/journal.pone.0075406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788802/
https://www.ncbi.nlm.nih.gov/pubmed/24098381
http://dx.doi.org/10.1371/journal.pone.0075406

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