Nicotinamide-mediated inhibition of SIRT1 deacetylase is associated with the viability of cancer cells exposed to antitumor agents and apoptosis

Silent mating-type information regulation 2, homolog 1 (SIRT1) represents an NAD(+)-dependent deacetylase that regulates the processes of stress response and cell survival. However, the functions of SIRT1 in stress- and drug-induced apoptosis remain elusive. The present study was designed to determi...

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Detalles Bibliográficos
Autores principales: WANG, TONG, CUI, HUIXIA, MA, NAN, JIANG, YOUHONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789038/
https://www.ncbi.nlm.nih.gov/pubmed/24137378
http://dx.doi.org/10.3892/ol.2013.1400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789038/
https://www.ncbi.nlm.nih.gov/pubmed/24137378
http://dx.doi.org/10.3892/ol.2013.1400

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