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Polymorphisms of GSTP1, ERCC2 and TS-3′UTR are associated with the clinical outcome of mFOLFOX6 in colorectal cancer patients

The aim of the current study was to examine whether polymorphisms in drug metabolism genes have any clinical impact on patients treated with 5-fluorouracil (FU)/oxaliplatin for metastatic colorectal cancer (MCRC). In total, 63 patients with MCRC were recruited and treated with a modified FOLFOX6 (mF...

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Detalles Bibliográficos
Autores principales: KUMAMOTO, KENSUKE, ISHIBASHI, KEIICHIRO, OKADA, NORIMICHI, TAJIMA, YUSUKE, KUWABARA, KOUKI, KUMAGAI, YOICHI, BABA, HIROYUKI, HAGA, NORIHIRO, ISHIDA, HIDEYUKI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789107/
https://www.ncbi.nlm.nih.gov/pubmed/24137384
http://dx.doi.org/10.3892/ol.2013.1467