USP2a alters chemotherapeutic response by modulating redox

Cancer cells are characterized by altered ubiquitination of many proteins. The ubiquitin-specific protease 2a (USP2a) is a deubiquitinating enzyme overexpressed in prostate adenocarcinomas, where it exhibits oncogenic behavior in a variety of ways including targeting c-Myc via the miR-34b/c cluster....

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Detalles Bibliográficos
Autores principales: Benassi, B, Marani, M, Loda, M, Blandino, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789164/
https://www.ncbi.nlm.nih.gov/pubmed/24071644
http://dx.doi.org/10.1038/cddis.2013.289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789164/
https://www.ncbi.nlm.nih.gov/pubmed/24071644
http://dx.doi.org/10.1038/cddis.2013.289

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