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The sodium/iodide symporter NIS is a transcriptional target of the p53-family members in liver cancer cells

Thyroid iodide accumulation via the sodium/iodide symporter (NIS; SLC5A5) has been the basis for the longtime use of radio-iodide in the diagnosis and treatment of thyroid cancers. NIS is also expressed, but poorly functional, in some non-thyroid human cancers. In particular, it is much more strongl...

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Detalles Bibliográficos
Autores principales: Guerrieri, F, Piconese, S, Lacoste, C, Schinzari, V, Testoni, B, Valogne, Y, Gerbal-Chaloin, S, Samuel, D, Bréchot, C, Faivre, J, Levrero, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789165/
https://www.ncbi.nlm.nih.gov/pubmed/24052075
http://dx.doi.org/10.1038/cddis.2013.302