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The sodium/iodide symporter NIS is a transcriptional target of the p53-family members in liver cancer cells
Thyroid iodide accumulation via the sodium/iodide symporter (NIS; SLC5A5) has been the basis for the longtime use of radio-iodide in the diagnosis and treatment of thyroid cancers. NIS is also expressed, but poorly functional, in some non-thyroid human cancers. In particular, it is much more strongl...
Autores principales: | Guerrieri, F, Piconese, S, Lacoste, C, Schinzari, V, Testoni, B, Valogne, Y, Gerbal-Chaloin, S, Samuel, D, Bréchot, C, Faivre, J, Levrero, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789165/ https://www.ncbi.nlm.nih.gov/pubmed/24052075 http://dx.doi.org/10.1038/cddis.2013.302 |
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