Cargando…

VDAC1-based peptides: novel pro-apoptotic agents and potential therapeutics for B-cell chronic lymphocytic leukemia

The voltage-dependent anion channel 1 (VDAC1), localized in the outer mitochondrial membrane, mediates metabolic cross-talk between the mitochondrion and the cytoplasm and thus serves a fundamental role in cell energy metabolism. VDAC1 also plays a key role in mitochondria-mediated apoptosis, intera...

Descripción completa

Detalles Bibliográficos
Autores principales: Prezma, T, Shteinfer, A, Admoni, L, Raviv, Z, Sela, I, Levi, I, Shoshan-Barmatz, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789174/
https://www.ncbi.nlm.nih.gov/pubmed/24052077
http://dx.doi.org/10.1038/cddis.2013.316