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Neoalbaconol induces energy depletion and multiple cell death in cancer cells by targeting PDK1-PI3-K/Akt signaling pathway

Many natural compounds derived from plants or microbes show promising potential for anticancer treatment, but few have been found to target energy-relevant regulators. In this study, we report that neoalbaconol (NA), a novel small-molecular compound isolated from the fungus, Albatrellus confluens, c...

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Detalles Bibliográficos
Autores principales: Deng, Q, Yu, X, Xiao, L, Hu, Z, Luo, X, Tao, Y, Yang, L, Liu, X, Chen, H, Ding, Z, Feng, T, Tang, Y, Weng, X, Gao, J, Yi, W, Bode, A M, Dong, Z, Liu, J, Cao, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789182/
https://www.ncbi.nlm.nih.gov/pubmed/24052072
http://dx.doi.org/10.1038/cddis.2013.324