Metastatic SW620 colon cancer cells are primed for death when detached and can be sensitized to anoikis by the BH3-mimetic ABT-737

Anoikis, a Bax-dependent apoptosis triggered by detachment from the extracellular matrix, is often inhibited in metastatic cancer cells. Using a couple of isogenic human colon cancer cell lines derived either from the primary tumor (SW480) or from a lymph node metastasis (SW620), we found that only...

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Detalles Bibliográficos
Autores principales: Maamer-Azzabi, A, Ndozangue-Touriguine, O, Bréard, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789186/
https://www.ncbi.nlm.nih.gov/pubmed/24030153
http://dx.doi.org/10.1038/cddis.2013.328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789186/
https://www.ncbi.nlm.nih.gov/pubmed/24030153
http://dx.doi.org/10.1038/cddis.2013.328

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