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Overexpression of 4EBP1, p70S6K, Akt1 or Akt2 differentially promotes Coxsackievirus B3-induced apoptosis in HeLa cells

Our previous studies have shown that the inhibition of phosphatidylinositol 3-kinase (PI3K) or mTOR complex 1 can obviously promote the Coxsackievirus B3 (CVB3)-induced apoptosis of HeLa cells by regulating the expression of proapoptotic factors. To further illustrate it, Homo sapiens eIF4E-binding...

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Detalles Bibliográficos
Autores principales: Li, X, Li, Z, Zhou, W, Xing, X, Huang, L, Tian, L, Chen, J, Chen, C, Ma, X, Yang, Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789189/
https://www.ncbi.nlm.nih.gov/pubmed/24030155
http://dx.doi.org/10.1038/cddis.2013.331