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Activation of TLR4 signaling promotes gastric cancer progression by inducing mitochondrial ROS production

Chronic infection, such as Helicobacter pylori infection, has been associated with the development of gastric cancer (GC). Pathogen-associated molecular patterns can trigger inflammatory responses via Toll-like receptors (TLRs) in GC. Here we showed that Toll-like receptor 4 (TLR4) was highly expres...

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Detalles Bibliográficos
Autores principales: Yuan, X, Zhou, Y, Wang, W, Li, J, Xie, G, Zhao, Y, Xu, D, Shen, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789192/
https://www.ncbi.nlm.nih.gov/pubmed/24030146
http://dx.doi.org/10.1038/cddis.2013.334