Systemic and Nonrenal Adverse Effects Occurring in Renal Transplant Patients Treated with mTOR Inhibitors

The mammalian target of rapamycin inhibitors (mTOR-I), sirolimus and everolimus, are immunosuppressive drugs largely used in renal transplantation. The main mechanism of action of these drugs is the inhibition of the mammalian target of rapamycin (mTOR), a regulatory protein kinase involved in lymph...

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Detalles Bibliográficos
Autores principales: Zaza, Gianluigi, Tomei, Paola, Ria, Paolo, Granata, Simona, Boschiero, Luigino, Lupo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789319/
https://www.ncbi.nlm.nih.gov/pubmed/24151517
http://dx.doi.org/10.1155/2013/403280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789319/
https://www.ncbi.nlm.nih.gov/pubmed/24151517
http://dx.doi.org/10.1155/2013/403280

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