Advanced Diabetic Nephropathy with Nephrotic Range Proteinuria: A Pilot Study of the Long-Term Efficacy of Subcutaneous ACTH Gel on Proteinuria, Progression of CKD, and Urinary Levels of VEGF and MCP-1

Background and Objective. Adrenocorticotropic hormone (ACTH) is able to reduce proteinuria in nondiabetic glomerulopathies through activation of melanocortin receptors (MCR) expressed in the podocyte. To determine the efficacy of ACTH, we conducted a randomized, open-label pilot trial of ACTH gel in...

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Detalles Bibliográficos
Autores principales: Tumlin, J. A., Galphin, C. M., Rovin, B. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789480/
https://www.ncbi.nlm.nih.gov/pubmed/24159603
http://dx.doi.org/10.1155/2013/489869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789480/
https://www.ncbi.nlm.nih.gov/pubmed/24159603
http://dx.doi.org/10.1155/2013/489869

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